Ketamine as Adjuvant for Acute Pain Management

Imani F, Varrassi G.
Ketamine as Adjuvant for Acute Pain Management.
Anesth Pain Med.9(6):e100178. doi: 10.5812/aapm.100178.


Peri-operative pain management is one of the important tasks of medical staff. The problems arising afterwards not only have a pathophysiological adverse effect on patients, but also detrimentally affect the health system, treatment costs, and delay in discharge, for which pain management should be planned prior to surgery, and the resulting stress (1-3).

Recent studies indicate a high incidence of persistent postoperative pain, and anesthesiologists should thus take proactive measures to control postoperative pain, particularly as some surgeries have more severe acute pain. Not only have a variety of drugs (such as opioids, NSAIDs, and adjuvants) been studied, but also several methods of administration (including oral, intravenous, epidural, inhalation, etc.) have been evaluated (4-6).

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L'Associazione Italiana per lo Studio del Dolore è il capitolo italiano dell'International Association for the Study of Pain IASP® e della European Pain Federation EFIC®